Dynasylan® for Pharmaceuticals and Chemical Synthesis

Wherever human health is concerned, it is important to meet the highest possible standards. Development of new pharmaceutical products demands a wide range of innovative fine chemicals. Our products are designed to meet the industriel demand for innovation, reliability, and quality.

Evonik is stocking special silanes in bulk quantities which are offered for multiple applications within the scope of advanced chemical syntheses:

Blocking agents

Dynasylan^® HMDS, Dynasylan^® BSA

Synthesis of lactam and macrolide antibiotics (penicillin and cephalosporin/erythromycin)
Synthesis of other active ingredients
In cholesterol-reducing drugs and agents to combat cancer

Further advantages of blocking agents

To improve reaction selectivity
To improve solubility in solvents
To improve stability during distillation
To improve applications for gas chromatography and mass spectrometry

Structure manipulation

Dynasylan^® TES => Reduction
Dynasylan^® TMSCN => a. o. Homologation

Beyond protective group technology

Reagents for cleaving functional groups, reducing agents, bases for organic synthesis
Advantages over purely organic reagents: Reaction under mild conditions, high yields, very good selectivity

Special purposes

Production of materials for column chromatography, e.g. modification of non-polar adsorption materials for purification of insulin and isolation of natural substances/active ingredients
Support for asymmetric heterogeneous catalysts

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